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The history and importance of the problem.Currently, although knowledge and medical technology with continuous progress. Enables users of health services has survived a serious illness, stress, and are in the hospital longer. Such a development, it makes people with mental illness are complex and require close supervision need to be in the ICU. But one of the major problems is that an infection while in the Hospital (Andrade, Gales, Gales, & Jones, 2003), such as a respiratory infection. In the blood stream infection. Infections urinary tract system and soft tissue. Infections in hospitals, said the number of infections that are caused by not less resistant to antibiotics and more rate (Clock, Cohen, Behta, Loss & Larson, et al 2010 Wareham;., 2008), is a disease that is causing the infection Staphylococcus aureus infections, such as the Methicillin-resistant (MRSA), extended-spectrum beta-lactamse (BSBL)-producing Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii resistant to several antibiotics in parallel (Milsontone, Bryant, Huskins, & Zerr, 2010)
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