It's elements, as well as lifestyle (e.g., low levels of exercise, lack of nutrients) and clinical criteria (such as illness, polypharmacy. Surgical PIN) can speed.
Unfavorable elements, including livelihoods. (Such as low levels of exercise, malnutrition) and clinical conditions. (Such as illness polypharmacy surgical fixation) can accelerate the process.
Elements of quality and way of life. Low level (such as exercise, nutrition) and clinical conditions (such as illness polypharmacy surgery freeze) can accelerate the process.