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Extraction techniques for capturing those SPE is required by, the substance caused interaction (interaction) caught on the solid phase. Do not use filters that exclude substances that are larger because there are solid-phase formation at the close. Make the acting solid contamination krongonuphak in aqueous solution at bring bite. But with solid particles filtered stuck at solid phase decreases the efficiency of extraction. Because they can cause obstruction (piugging and Channeling), and sometimes a substance that may catch or complex substances is that these particles cannot be washed out.
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